Fluconazole for the treatment of Cryptococcus neoformans meningitis in an immunocompetent host.
نویسندگان
چکیده
We present a case of a 23-year-old immunocompetent male who presented with chronic meningitis and was diagnosed as cryptococcal meningitis by positive cryptococcal antigen titer. The cerebrospinal fluid culture was positive for Cryptococcus neoformans. He was treated initially with amphotericin B but was later changed to fluconazole due to toxicity. This case highlights the use of fluconazole to successfully treat chronic meningitis in an immunocompetent host.
منابع مشابه
Successful treatment of Cryptococcus neoformans immune reconstitution inflammatory syndrome in an immunocompetent host using thalidomide
Immune reconstitution inflammatory syndrome (IRIS) can complicate antifungal treatment of cryptococcosis. There are limited data on managing cryptococcal-associated IRIS. We describe an immunocompetent patient who developed IRIS complicating Cryptococcus neoformans meningitis, successfully treated with thalidomide following failure of corticosteroid therapy. Data on thalidomide use in cryptococ...
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متن کامل[Cutaneous cryptococcosis in an immunocompetent host].
An immunocompetent 62-year-old woman presented with cutaneous lesions over her right arm and the hypogastrium. The diagnosis of cutaneous cryptococcosis was made on the basis of the demonstration and isolation of Cryptococcus neoformans from the aspirated pus. The patient responded to fluconazole treatment.
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Introduction Cryptococcus neoformans has emerged as a clinically important opportunistic pathogen worldwide due to the AIDS pandemic. This pathogenic yeast causes pulmonary and systemic cryptococcosis in immucompromised human and susceptible animals such as cats and dogs (8, 10). C. neoformans is globally distributed and found to associate with soil, pigeon excreta, and decaying wood. Cryptococ...
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ورودعنوان ژورنال:
- Neurosciences
دوره 8 2 شماره
صفحات -
تاریخ انتشار 2003